Medical Biochemistry: Metabolism of Fats and Lipids

Explore the fascinating world of fats and lipids metabolism with this comprehensive course! We'll embark on a detailed journey, starting with fat digestion and absorption in the intestines, following the path of absorbed fats as chylomicrons to their utilization by body cells.

Discover how your body synthesizes and packages fats as lipoproteins after consuming a high-carbohydrate meal. We'll delve into the intricate processes of lipid metabolism during a fasting state, examining lipid mobilization and fatty acid oxidation.

This course is structured into four engaging sections, featuring approximately 18 lecture videos, culminating in a review of clinical case questions related to fats and lipids metabolism.

Here's a breakdown of the key topics covered:

• Digestion & Absorption:
  • Eating Food Rich in Fats & Lipids: A foundational overview.
  • Absorption of Digested Fats as Chylomicrons: Understanding the chylomicron pathway.
  • Steatorrhea: Exploring the causes and implications of fat malabsorption.
• Metabolic Pathways:
  • Eating High Carbohydrate Meals: Focus on fatty acids biosynthesis, triglyceride synthesis, and cholesterol synthesis.
  • Lipoproteins Metabolism: A deep dive into LDL receptors and hyperlipidaemias.
  • Fasting State: Understanding lipid mobilization and fatty acid oxidation, including peroxisomal oxidation of VLCFA and fatty acids transport into the mitochondria.
  • Beta Oxidation of Fatty Acids: The primary pathway for fatty acid breakdown.
  • Oxidation of Odd Chain Fatty Acids: A specialized oxidation process.
  • Ketone Bodies Metabolism: Understanding ketone body production during fasting.
• Lipid Building Blocks:
  • Phospholipids: Their structure and function.
  • Sphingolipids & Sphingolipidoses: Exploring sphingolipid metabolism and associated disorders.
  • Eicosanoids: Understanding the role of eicosanoids in inflammation and other processes.

Prepare for clinical scenarios with our clinical multiple-choice question review focused on fats and lipids metabolism. This course provides a thorough understanding of how your body handles fats and lipids, crucial for healthcare professionals and students alike.